The actress and humanitarian tested positive for a BRCA1 gene mutation, which significantly increases the risk of developing breast and ovarian cancer.
Angelina Jolie - BRCA1 Gene Mutation
Hanks carries the thalassemia trait, a genetic condition affecting the production of hemoglobin and causing mild anemia.
Tom Hanks - Thalassemia Trait
The Olympic swimmer has Marfan syndrome, a genetic disorder that affects connective tissues and can result in long limbs and a flexible body.
Michael Phelps - Marfan Syndrome
The actor and comedian reportedly has a rare genetic condition known as Atkinson's Syndrome, which causes him to have a unique appearance and speech patterns.
Rowan Atkinson - Atkinson's Syndrome
Garcia has syndactyly, a genetic condition where fingers or toes are fused together, usually in the form of webbing.
Andy Garcia - Syndactyly
Aykroyd has heterochromia, a condition where the irises of the eyes have different colors, giving his eyes a distinct and striking appearance.
Dan Aykroyd - Heterochromia
The stunt performer and TV personality was born with a congenital limb deficiency, which resulted in the partial amputation of one of his hands.
Steve-O - Congenital Limb Deficiency
Bosworth also has heterochromia, with one eye being blue and the other being hazel, contributing to her unique and captivating look.
Kate Bosworth - Heterochromia
Whitaker has ptosis, a condition where the upper eyelid droops, adding to his distinctive and expressive appearance.
Forest Whitaker - Ptosis
Walken has Dupuytren's contracture, a condition where the connective tissue in the hand thickens, causing the fingers to bend inward.
Christopher Walken - Dupuytren's Contracture